ISOMURA LABORATORY, Tamagawa University Brain Science Institute

アライン・アントニオ・リオス・ダビラ Alain Antonio Ríos Dávila

研究内容

The motor features of Parkinson’s disease have been attributed in part to the reduction of dopamine in the basal ganglia. These features are the result of a complex neuronal disorder at different levels of the SNC, such as changes in the neuronal excitability, synchronized oscillatory activity, and abnormal sensory responses of areas of the cerebral cortex that are involved in planning and execution of movement, as well as executive, limbic and sensory functions. The adequately characterization of these changes will increase our understanding of both normal and pathological neuronal activity, and will help to develop more specific and effective treatments for parkinsonian patients.

[ 連絡先 ]　

略歴

2005年3月　C.E.C.y T. 6. Miguel Othón de Mendizabal. IPN.　卒業
2012年3月　Medical School. National Polytechnic Institute.(MD)　卒業
2014年3月　Medical School. National Polytechnic Institute.(修士)　修了
2016年9月～ 玉川大学 脳科学研究科 脳科学専攻(博士後期課程)

原著論文

Dopamine-dependent modulation of rat globus pallidus excitation by nicotine acetylcholine receptors.

Ríos A, Barrientos R, Alatorre A, Delgado A, Perez-Capistran T, Chuc-Meza E, García-Ramirez M, Querejeta E.

Exp Brain Res. 2016. Feb;234(2):605-16.

The local application of a flavonoid, (-)-epicatechin, increases the spiking of globus pallidus neurons in a dose-dependent manner and diminishes the catalepsy induced by haloperidol.

Alatorre A, Oviedo-Chávez A, Villalobos N, Ríos A, Barrientos R, Querejeta E.

Behav Pharmacol. 2015. Feb;26(1-2):117-24

Striatal input- and rate-dependent effects of muscarinic receptors on pallidal firing.

Querejeta E, Alatorre A, Ríos A, Barrientos R, Oviedo-Chávez A, Bobadilla-Lugo RA, Delgado A.

ScientificWorldJournal. 2012. ;2012:547638

国内学会発表

Effect of dopamine depletion of striatum on functional activity of motor cortex neurons in the rat.
Alain Rios, Shogo SOMA, Junichi YOSHIDA, Masanori KAWABATA, Yutaka SAKAI, Yoshikazu ISOMURA
第40回日本神経科学大会　(幕張)　2017年7月20日

Polytechnic Research Congress. National Polytechnic Institute(Mexico City) 2013年

XXV Pharmacology Mexican Association Congress.(Mexico City) 2012年

I National Physiological Sciences Congress.(Mexico City) 2011年

Third Academic Reunion of the Department of Physiology, Biophysics and Neuroscience at CINVESTAV.(Mexico City) 2011年

受賞

玉川大学脳科学ワークショップ(第7回) 2017年9月28日
優秀発表賞
Loss of laterality for forelimb-movements in motor cortex in a hemiparkisonian rat model.

玉川大学脳科学ワークショップ(第6回) 2017年2月17日
奨励賞
Effects of dopamine depletion of striatum on functional activity of motor cortex neurons.

2016年度 日本政府(文部科学省)奨学金留学生(研究留学生)

プライベート

1988年生まれ。メキシコ出身。医師。